We read the recent article of Magalhães da Silva et al1 reporting the correlation between biogeographic ancestries, estimated using 30 ancestry informative markers (AIMs), and self-reported skin color in two different Brazilian Northeastern populations (Fortaleza and Salvador, capitals of the states of Ceará and Bahia, respectively). The authors observed that African ancestry is more correlated in the sample from Salvador than in the one from Fortaleza and that the use of different African populations as proxies of the Brazilian’s African ancestors may influence the results.
One unusual point of this study was taking Han Chinese from Beijing (CHB) as pseudo-ancestors for Amerindians as there is no Native American population included in the HapMap Project (http://hapmap.ncbi.nlm.nih.gov/) and, in addition, because CHB population has been shown to have allele frequencies similar to those of Native Amerindians….
- Ronald R de Moura, Valdir de Queiroz Balbino, Sergio Crovella and Lucas A C Brandão (2016). LETTER: On the use of Chinese population as a proxy of Amerindian ancestors in genetic admixture studies with Latin American populations. European Journal of Human Genetics, 24(3), 326-327.
Peoples: Native Americans | Places: Brazil, China, Fortaleza, and Salvador | Topics: Admixture analysis and Ancestry informative markers | DNA Type: Autosomal DNA