Construction of human Y-chromosomal haplotypes using a new polymorphic A to G transition

Construction of human Y-chromosomal haplotypes using a new polymorphic A to G transition

Abstract:

We report the discovery of a polymorphic A to G transition found on the human Y chromosome by sequencing Y-specific sequence-tagged sites (STSs). It shows maximal linkage disequilibrium with a previously described Alu insertional polymorphism. We analyze further an apparently African Y chromosome which seems to have entered a Mexican Mayan population several generations ago. Using the newly discovered transition and the Y-speclfic polymorphic Alu insertion, we discuss how the chromosome’s haplotype information might be used to answer questions of houman origins and migrations.

Citation:

  • Selelstad, Mark T.; Hebert, Joan M.; Lin, Alice A.; UnderhllI, Peter A.; Ibrahlm, Muntaser; Vollrath, Douglas & Cavalll-Storza (1994). Construction of human Y-chromosomal haplotypes using a new polymorphic A to G transition. Human Molecular Genetics, 3(12), 2159-2161.

Source Link:
http://www.dx.doi.org/10.1093/hmg/3.12.2159

Keywords

Peoples: - | Places: - | Topics: - | DNA Type: Y-DNA

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