The knowledge of mutation rate at Y-STR markers is essential in forensic casework, especially kinship genetic studies. In the present study, one hundred father–son pairs from Chinese Han population were typed with 53 Y STR markers (38 conventional markers and 15 rapidly mutating markers). A total of 28 mutations were detected in 6201 allele transfers. All were one-step mutation. The average estimated mutation rate of 15 rapidly mutating (RM) Y-STRs was 1.05 × 10−2 (95% CI 5.45 × 10−3–1.39 × 10−2), while the average mutation rate of 38 conventional Y-STRs was 1.46 × 10−3 (95% CI 3.07 × 10−4–2.59 × 10−3). In summary, the average mutation rate of 15 RM Y-STRs seemed to be seven times higher than that of 38 conventional Y-STRs.
- Lang, M., Ye, Y., Li, J., Zhang, Y., Yuan, T. and Hou, Y. (2017). Comprehensive Mutation Analysis of 53 Y-STR Markers in Father-Son Pairs. Forensic Science International: Genetics Supplement Series, in press, in press.
Peoples: - | Places: - | Topics: AGCU database Y24, AGCU Y SUPP, Mutation rate, Rapidly mutating Y-STRs (RM Y-STRs), and Y-STRs | DNA Type: Y-DNA