Analysis of two polymorphic regions of mitochondrial DNA obtained from T. N. Kulikovskii-Romanov, the nephew of the last Tsar of the Russian Empire Nikolai II Romanov, was performed. The mitochondrial DNA sequences of T. N. Kulikovskii-Romanov and earlier reported DNA sequences obtained from the putative remains of Nikolai II showed almost complete coincidence except for a single nucleotide at the position 16169. At this position, C was found in mitochondrial DNA of T. N. Kulikovskii-Romanov, C/T in that from the putative remains of Nikolai II Romanov, and T in mitochondrial DNA from great great grandson and great great grand-daughter of Louise Hesse-Cassel. These data suggest independent mutations in the maternal lineage of Louise Hesse-Cassel’s descendants and/or a mutation leading to a heteroplasmia in the lineage of Louise Hesse-Cassel.
- Rogaev, E. I.; Ovchinnikov, I. V.; Dzhorzh-Khislop, P. & Rogaeva, E. A. (1996). Comparison of mitochondrial DNA sequences of TN Kulikovskiui-Romanov, the nephew of Tsar Nikolaui II Romanov, with DNA from the putative remains of the Tsar. Genetika, 32(12), 1690-2.
Peoples: - | Places: - | Topics: - | DNA Type: mtDNA