Carriers of mitochondrial DNA macrohaplogroup R colonized Eurasia and Australasia from a southeast Asia core area

Coeval independently dispersals around 50 kya of the West Asia haplogroup U and the Wallacea haplogroup P, points to a halfway core area in southeast Asia as the most probable centre of expansion of macrohaplogroup R, what fits in the phylogeographic pattern of its ancestor, macrohaplogroup N, for which a northern route and a southeast Asian origin has been already proposed.

2017-05-27T08:22:26+00:00May 27th, 2017|

A genomic history of Aboriginal Australia

We estimate that Aboriginal Australians and Papuans diverged from Eurasians 51–72 kya, following a single out-of-Africa dispersal, and subsequently admixed with archaic populations. Finally, we report evidence of selection in Aboriginal Australians potentially associated with living in the desert.

2016-09-28T13:26:17+00:00September 28th, 2016|

An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia

We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.

2017-06-18T16:35:16+00:00July 3rd, 2016|

Ancient mtDNA sequences from the First Australians revisited

The publication in 2001 by Adcock et al., [Adcock GJ, et al., (2001) Proc Natl Acad Sci USA 98(2):537–542] in PNAS reported the recovery of short mtDNA sequences from ancient Australians, including the 42,000-y-old Mungo Man [Willandra Lakes Hominid (WLH3)]. This landmark study in human ancient DNA suggested...

2016-06-11T05:08:24+00:00June 11th, 2016|

S

Haplogroup S is a branch on the maternal tree of human kind. Its age is between 48,000 and 59,000 years (Behar et al., 2012b).

2018-10-08T16:31:37+00:00June 6th, 2016|

Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis

Published and new samples of Aboriginal Australians and Melanesians were analyzed for mtDNA (n = 172) and Y variation (n = 522), and the resulting profiles were compared with the branches known so far within the global mtDNA and the Y chromosome tree. (i) All Australian lineages are confirmed to fall within the mitochondrial founder branches M and N and the Y chromosomal founders C and F, which ar

2018-09-26T17:24:13+00:00December 31st, 2007|

South Asia, the Andamanese, and the Genetic Evidence for an Early “Human Dispersal out of Africa”

The out-of-Africa model of anatomically modern human evolution posits an African origin 100,000– - 200,000 years ago, followed by subsequent dispersal(s) to Eurasia and other continents within the last 100,000 years (Stringer and Andrews 1988). Although alternative models have been proposed, the out-of-Africa scenario receives the most support both from archeological and genetic evidence (Lahr and Foley 1994). However, the route(s) followed by the African migrants remain poorly understood...

2016-06-09T19:26:56+00:00December 31st, 2003|
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