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Age: 1,047.3 ± 4,500.8; CI=95% (Behar et al., 2012b)
Origin: Western Eurasia
Mutations: C394T C16260T T16356C
FTDNA Tree: Link
Parent Branch: U2e1’2’3
Descendant branch(s): U2e3a


Haplogroup U2e3 is a branch on the maternal tree of human kind. The woman who started this branch lived at some point between recent generations and 5,500 years ago (Behar et al., 2012b).

Information on this lineage comes from one sample from the genetic genealogy community with an origin in Italy (Greenspan 2006 – 2016).

There are two members of the lineage in the Gene 2 data set, but neither has entered demographic information.

mtDNA Haplogroup U2e3 Phylotree History

Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.

Build# Called Mutations Notes
14 U2e3 C309d C394T C575T C3170a T15721C A16181G C16260T T16356C Released 5 Apr 2012; First version to use the RSRS
15 U2e3 C394T C16260T T16356C Released 30 Sep 2012
16 U2e3 C394T C16260T T16356C Released 19 Feb 2014
17 U2e3 C394T C16260T T16356C Released 18 Feb 2016

mtDNA Haplogroup U2e3 Data Sources

GenBank Samples

GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.

Note: GenBank results currently use Phylotree build 16. I am working on changing resuts over to build 17.

Hg IDPublicationMissing VariantsAdditional Variants
Hap5008414 Greenspan et al., 2006 - 2016 U2e3:217 U2e3:315.1C, 15758, 15911, 16129C, 16182C, 16183C, 16400

Geno 2.0 Data

Data from Geno 2.0 is derived from the The National Geographic Society’s Genographic Project — the DAR. The Hg ID is specific to this site and is used to protect the identities of those who take part in Genographic research. Birth Country, Mother's Birth Country, and Maternal Grandmother's Birth Country have been normalized from DAR database fields. The Maternal Origin is determined based on the three previous fields.

Note: Geno 2.0 results currently use Phylotree build 16. I am working on changing resuts over to build 17.

Hg IDBirth
Birth Country
Maternal Grandmother's
Birth Country

If you use the information in this table, please credit both this site and The National Geographic Society’s Genographic Project.

Sources & Resources

Related Sources

Additional Resources

mtDNA Consultants

The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.


Peoples: Italian | Places: Italy

Last Updated: Last updated: August 30, 2016 at 6:03 am

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