V

Haplogroup V is a branch on the maternal tree of human kind. It is a child of haplogroup HV0a. It was likely born around 9,800 years ago. (Behar et al., 2012b)

Origin

MtDNA haplogroup V was likely born in West Asia. It may also have been born in Europe.

Age

Behar et al., 2012b placed the birth of the V lineage between 8,400 and 11,100 years ago. This means the line was born in the Mesolithic or the Neolithic. At the time, people were using highly refined stone tools. They were just starting to adopt farming culture.

Ancient DNA

Coming Soon

Timeline

This timeline is an overview of the V branch’s history from the first early people to the birth of the first woman from the V lineage. (View in new tab.)

mtDNA Haplogroup V Phylotree History

Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.

Build#	Called	Variants (Mutations)	Notes
01	V	4580	Released 27 Aug 2008
02	V	4580	Released 14 Oct 2008
04	V	4580	Released 10 May 2009
05	V	4580	Released 8 Jul 2009
06	V	4580	Released 28 Sep 2009
07	V	4580	Released 10 Nov 2009
08	V	4580	Released 21 Mar 2010
09	V	4580	Released 20 Jun 2010
10	V	4580	Released 10 Aug 2010
11	V	4580	Released 7 Feb 2011
12	V	4580	Released 20 Jul 2011
13	V	4580	Released 28 Dec 2011; Last Build to use the rCRS
14	V	G4580A	Released 5 Apr 2012; First version to use the RSRS
15	V	G4580A	Released 30 Sep 2012
16	V	G4580A	Released 19 Feb 2014
17	V	G4580A	Released 18 Feb 2016

mtDNA Haplogroup V Data Sources

GenBank Samples

GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.

Note: GenBank results currently use Phylotree build 16. I am working on changing results over to build 17.

Hg ID	Origin	Publication	Hg BLD16	Hg BLD17	Hg YFull	Missing Variants	Additional Variants
Hap5000007	Italy	Achilli et al., 2004	V		V*	none	V:309.1CC, 315.1C, 437, 11674, 14800, 16320, 16519
Hap5001296		Behar et al., 2012b	V		V-c*	V:72	V:309.1C, 315.1C, 15849, 16519
Hap5002159		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 9804, 16519
Hap5002734		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 15924, 16519
Hap5002848		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 12451, 16519
Hap5003354		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 10376, 15894, 16519
Hap5003363		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 4452, 16519
Hap5003374		Behar et al., 2012b	V		V*	none	V:41, 309.1C, 315.1C, 3396, 6956, 16239, 16399, 16519
Hap5003377		Behar et al., 2012b	V		V-b*	V:16298	V:315.1C, 4853, 11318G, 14750, 16519
Hap5003405		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 8239, 15924, 16519
Hap5003445		Behar et al., 2012b	V		V-b*	V:16298	V:315.1C, 533, 16519
Hap5003698		Behar et al., 2012b	V		V24	V:16298	V:315.1C, 3335, 3573, 11151, 11260, 16519
Hap5003981		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 3398, 16519
Hap5004125		Behar et al., 2012b	V		V-c*	V:72	V:309.1C, 315.1C, 16093, 16519
Hap5004287		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 13708, 16168, 16519
Hap5004318		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 11914R, 16519
Hap5004356		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 16291, 16519
Hap5004444		Behar et al., 2012b	V		V*	none	V:309.1CC, 315.1C, 10685, 16519
Hap5004611		Behar et al., 2012b	V		V*	none	V:194, 309.1C, 315.1C, 12813, 16218, 16519
Hap5004631		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 11063, 16519
Hap5004667		Behar et al., 2012b	V		V*	none	V:309.1CC, 315.1C, 2746, 3290, 6378, 9142C, 16233C, 16519
Hap5004835		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 5813d, 5902, 16519
Hap5004968		Behar et al., 2012b	V		V-c*	V:72	V:309.1CC, 315.1C, 16192, 16325, 16519
Hap5004972		Behar et al., 2012b	V		V*	none	V:309.1C, 315.1C, 480, 13015, 15854Y
Hap5005099		Behar et al., 2012b	V		V*	none	V:64, 309.1CC, 315.1C, 7056R, 15848, 16519, 16527

Sources & Resources

Related Sources

   

• Achilli, A., Rengo, C., Magri, C., Battaglia, V., Olivieri, A., Scozzari, R., Moral, P. (2004). The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool. American journal of human genetics, 75(5), 910-918.
• Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
• Bertolin, C., Magri, C., Barlati, S., Vettori, A., Perini, G.I., Peruzzi, P., Mostacciuolo, M.L. and Vazza, G. (2011). Analysis of complete mitochondrial genomes of patients with schizophrenia and bipolar disorder. Journal of Human Genetics, 56(12), 869-872.
• Cardoso, S., Valverde, L., Alfonso-Sánchez, M.A., Palencia-Madrid, L., Elcoroaristizabal, X., Algorta, J., Catarino, S., Arteta, D., Herrera, R.J., Zarrabeitia, M.T. and Peña, J.A. (2013). The Expanded mtDNA Phylogeny of the Franco-Cantabrian Region Upholds the Pre-Neolithic Genetic Substrate of Basques. PLoS ONE, 8(7), e67835.
• Coble, M.D., Just,R.S., O'Callaghan, J.E., Letmanyi, I.H., Peterson,C.T., Irwin,J.A. and Parsons,T.J. (2004). Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians. International journal of legal medicine, (3),, 137-146.
• Derenko, M., Malyarchuk, B., Bahmanimehr, A., Denisova, G., Perkova, M., Farjadian, S., & Yepiskoposyan, L. (2013). Complete Mitochondrial DNA Diversity in Iranians. PLoS ONE, 8(11), e80673.
• Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
• Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
• Finnilä, S., Lehtonen, M.S. and Majamaa, K. (2001). Phylogenetic Network for European mtDNA. American journal of human genetics, 68(6), 1475-1484.
• Fraumene, C., Belle, E.M., Castrì, L., Sanna, S., Mancosu, G., Cosso, M., Marras, F., Barbujani, G., Pirastu, M. and Angius, A. (2006). High Resolution Analysis and Phylogenetic Network Construction Using Complete mtDNA Sequences in Sardinian Genetic Isolates. Molecular Biology and Evolution, 23(11), 2101-2111.
• FamilyTreeDNA & Greenspan (2006). Sequences Directly Submited by FamilyTreeDNA on Customers’ Behalf. , -, -.
• Hartmann, A., Thieme, M., Nanduri, L.K., Stempfl, T., Moehle, C., Kivisild, T. and Oefner, P.J. (2008). Validation of microarray-based resequencing of 93 worldwide mitochondrial genomes. Human mutation, 30(1), 115-122.
• Ingman, M., Kaessmann, H., Pääbo, S., & Gyllensten, U. (2000). Mitochondrial genome variation and the origin of modern humans. Nature, 408(6813), 708-713.
• Kloss-Brandstätter, A., Schäfer, G., Erhart, G., Hüttenhofer, A., Coassin, S., Seifarth, C., Summerer, M., Bektic, J., Klocker, H. and Kronenberg, F. (2010). Somatic Mutations throughout the Entire Mitochondrial Genome Are Associated with Elevated PSA Levels in Prostate Cancer Patients. The American Journal of Human Genetics, 87(6), 802-812.
• Maca-Meyer, N., González, A.M., Larruga, J.M., Flores, C. and Cabrera, V.M. (2001). Major genomic mitochondrial lineages delineate early human expansions. BMC Genetics, 2(1), 1.
• Pereira, L., Gonçalves, J., Franco-Duarte, R., Silva, J., Rocha, T., Arnold, C., Richards, M. and Macaulay, V. (2007). No Evidence for an mtDNA Role in Sperm Motility: Data from Complete Sequencing of Asthenozoospermic Males. Molecular Biology and Evolution, 24(3), 868-874.
• Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J.S., Bezrukov, V. and Blanché, H. (2014). The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging cell, 13(3), 401-407.
• Seoane, M., Mosquera-Miguel, A., Gonzalez, T., Fraga, M., Salas, A. and Costoya, J.A. (2011). The Mitochondrial Genome Is a “Genetic Sanctuary” during the Oncogenic Process. PLoS ONE, 6(8), e23327.
• Sequeira, A., Rollins, B., Magnan, C., van Oven, M., Baldi, P., Myers, R.M., Barchas, J.D., Schatzberg, A.F., Watson, S.J., Akil, H. and Bunney, W.E. (2015). Mitochondrial Mutations in Subjects with Psychiatric Disorders. PLoS ONE, 10(5), e0127280.
• Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
• Zheng, H. X., Yan, S., Qin, Z. D., & Jin, L. (2012). MtDNA analysis of global populations support that major population expansions began before Neolithic Time. Nature Scientific Reports, 2, -.

Additional Resources

• Ian Logan’s mtDNA Pages
• Ian Logan’s Instructions for mtGenome Genbank Donation
• James Lick’s mtDNA Utility
• The FTDNA Haplogroup Project for Haplogroup V
• The Wikipedia Article for Haplogroup V

mtDNA Consultants

The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.

• DNA Explorers – Robert Sliwinski
• Genetic Genealogy Consultant – Ugo Perego
• Your DNA Guide – Diahan Southard