Haplogroup H5s is a branch on the maternal tree of human kind. The woman who started this branch lived at some point between recent generations and 7,200 years ago (Behar et al., 2012b).
mtDNA Haplogroup H5s Phylotree History
Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.
|14||H5s||T5302C G16391A||Released 5 Apr 2012; First version to use the RSRS|
|15||H5s||T5302C G16391A||Released 30 Sep 2012|
|16||H5s||T5302C G16391A||Released 19 Feb 2014|
|17||H5s||T5302C G16391A||Released 18 Feb 2016|
mtDNA Haplogroup H5s Data Sources
GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.
Note: GenBank results currently use Phylotree build 16. I am working on changing results over to build 17.
|Hg ID||Origin||Publication||Hg BLD16||Hg BLD17||Hg YFull||Missing Variants||Additional Variants|
|Hap5002468||-||Behar et al., 2012b||H5s||-||none||H5s:309.1CC, 315.1C, 12972, 16519|
|Hap5002624||-||Behar et al., 2012b||H5s||-||none||H5s:309.1C, 315.1C, 3666, 16519|
|Hap5002747||-||Behar et al., 2012b||H5s||-||H5s:73||H5s:309.1C, 315.1C, 16519|
|Hap5002905||-||Behar et al., 2012b||H5s||-||none||H5s:309.1C, 315.1C, 16519|
|Hap5003630||-||Behar et al., 2012b||H5s||-||none||H5s:309.1C, 315.1C, 573.1XC, 3666, 16519|
|Hap5013123||-||Raule et al., 2014||H5s||-||none||H5s:309.1CC, 315.1C, 6448A, 16519|
|Hap5013885||-||Santoro et al., 2010||H5s||-||none||H5s:310, 316C, 15001, 15213, 16519|
|Hap5022841||Zheng et al., 2012||H5s||none||H5s:315.1C, 16311N, 16519|
Sources & Resources
- Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
- Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
- Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
- Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J.S., Bezrukov, V. and Blanché, H. (2014). The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging cell, 13(3), 401-407.
- Santoro, A., Balbi, V., Balducci, E., Pirazzini, C., Rosini, F., Tavano, F., Achilli, A., Siviero, P., Minicuci, N., Bellavista, E. and Mishto, M. (2010). Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer’s Disease. PLoS ONE, 5(8), e12037.
- Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
- Zheng, H. X., Yan, S., Qin, Z. D., & Jin, L. (2012). MtDNA analysis of global populations support that major population expansions began before Neolithic Time. Nature Scientific Reports, 2, -.
- Ian Logan’s mtDNA Pages
- Ian Logan’s Instructions for mtGenome Genbank Donation
- James Lick’s mtDNA Utility
- The FTDNA Haplogroup Project for Haplogroup H & HV
- The Wikipedia Article for Haplogroup H
The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.
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