H1

Summary

Age: 9,888.6 ± 880.6; CI=95% (Behar et al., 2012b)
Origin: West Asia
Mutations: G3010A
FTDNA Tree: Link
Parent Branch: H
Descendant branch(s): H1a H1aa H1ab H1ac H1ad H1ae H1af H1ag H1ah H1ai H1aj H1ak H1am H1an H1ao H1ap H1aq H1ar H1as H1at H1au H1av H1aw H1ax H1ay H1az H1b H1ba H1bb H1bc H1bd H1be H1bf H1bg H1bh H1bi H1bj H1bk H1bm H1bn H1bo H1bp H1bq H1br H1bs H1bt H1bu H1bv H1bw H1bx H1bz H1c H1ca H1cc H1cd H1cf H1cg H1ch H1ci H1cj H1ck H1e H1f H1g H1h H1i H1j H1k H1m H1n H1o H1p H1q H1r H1s H1t H1u H1v H1w H1x H1y H1z

Background

Haplogroup H1 is a branch on the maternal tree of human kind. The woman who founded this line lived between 9,000 and 10,800 years ago (Behar et al., 2012b).

National Geographic Geno 2.0 Text

mtDNA Haplogroup H1 Phylotree History

Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.

mtDNA Haplogroup H1 Data Sources

GenBank Samples

GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.

Note: GenBank results currently use Phylotree build 16. I am working on changing resuts over to build 17.

Geno 2.0 Data

Data from Geno 2.0 is derived from the The National Geographic Society’s Genographic Project — the DAR. The Hg ID is specific to this site and is used to protect the identities of those who take part in Genographic research. Birth Country, Mother's Birth Country, and Maternal Grandmother's Birth Country have been normalized from DAR database fields. The Maternal Origin is determined based on the three previous fields.

Note: Geno 2.0 results currently use Phylotree build 16. I am working on changing resuts over to build 17.

If you use the information in this table, please credit both this site and The National Geographic Society’s Genographic Project.

Sources & Resources

Related Sources

• Achilli, A., Rengo, C., Magri, C., Battaglia, V., Olivieri, A., Scozzari, R., Moral, P. (2004). The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool. American journal of human genetics, 75(5), 910-918.
• Behar, D.M., Harmant, C., Manry, J., van Oven, M., Haak, W., Martinez-Cruz, B., Salaberria, J., Oyharçabal, B., Bauduer, F., Comas, D. and Quintana-Murci, L. (2012). The Basque Paradigm: Genetic Evidence of a Maternal Continuity in the Franco-Cantabrian Region since Pre-Neolithic Times. American journal of human genetics, 90(3), 486-493.
• Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
• Brotherton, P., Haak, W., Templeton, J., Brandt, G., Soubrier, J., Adler, C.J., Richards, S.M., Der Sarkissian, C., Ganslmeier, R., Friederich, S. and Dresely, V. (2013). Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans. Nature Communications, 4, 1764+.
• Cardoso, S., Valverde, L., Alfonso-Sánchez, M.A., Palencia-Madrid, L., Elcoroaristizabal, X., Algorta, J., Catarino, S., Arteta, D., Herrera, R.J., Zarrabeitia, M.T. and Peña, J.A. (2013). The Expanded mtDNA Phylogeny of the Franco-Cantabrian Region Upholds the Pre-Neolithic Genetic Substrate of Basques. PLoS ONE, 8(7), e67835.
• Coble, M.D., Just,R.S., O'Callaghan, J.E., Letmanyi, I.H., Peterson,C.T., Irwin,J.A. and Parsons,T.J. (2004). Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians. International journal of legal medicine, (3),, 137-146.
• Costa, M.D., Cherni, L., Fernandes, V., Freitas, F., el Gaaied, A.B.A. and Pereira, L. (2009). Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity. , 130(4), 222-226.
• Derenko, M., Malyarchuk, B., Bahmanimehr, A., Denisova, G., Perkova, M., Farjadian, S., & Yepiskoposyan, L. (2013). Complete Mitochondrial DNA Diversity in Iranians. PLoS ONE, 8(11), e80673.
• Ennafaa, H., Cabrera, V.M., Abu-Amero, K.K., González, A.M., Amor, M.B., Bouhaha, R., Dzimiri, N., Elgaaïed, A.B. and Larruga, J.M. (2009). Mitochondrial DNA haplogroup H structure in North Africa. BMC Genetics, 10(1), 1.
• Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
• Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
• Fraumene, C., Belle, E.M., Castrì, L., Sanna, S., Mancosu, G., Cosso, M., Marras, F., Barbujani, G., Pirastu, M. and Angius, A. (2006). High Resolution Analysis and Phylogenetic Network Construction Using Complete mtDNA Sequences in Sardinian Genetic Isolates. Molecular Biology and Evolution, 23(11), 2101-2111.
• Fregel, Rosa; Pestano, Jose; Arnay, Matilde; Cabrera, Vicente M.; Larruga, Jose M. & Gonzalez, Ana M. (2009). The maternal aborigine colonization of La Palma (Canary Islands). European Journal of Human Genetics, 17(10), 1314-1324.
• Gasparre, G., Porcelli, A.M., Bonora, E., Pennisi, L.F., Toller, M., Iommarini, L., Ghelli, A., Moretti, M., Betts, C.M., Martinelli, G.N. and Ceroni, A.R. (2007). Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors. Proceedings of the National Academy of Sciences, 104(21), 9001-9006.
• Gómez-Durán, A., Pacheu-Grau, D., López-Gallardo, E., Díez-Sánchez, C., Montoya, J., López-Pérez, M.J. and Ruiz-Pesini, E. (2010). Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups. Human Molecular Genetics, 19(17), 3343-3353.
• Family Tree DNA & Greenspan (2006). Sequences Directly Submited by Family Tree DNA on Customers’ Behalf. , -, -.
• Maca-Meyer, N., González, A.M., Larruga, J.M., Flores, C. and Cabrera, V.M. (2001). Major genomic mitochondrial lineages delineate early human expansions. BMC Genetics, 2(1), 1.
• Malyarchuk, B., Derenko, M., Grzybowski, T., Perkova, M., Rogalla, U., Vanecek, T. and Tsybovsky, I. (2010). The Peopling of Europe from the Mitochondrial Haplogroup U5 Perspective. PLoS ONE, 5(4), e10285+.
• McMahon, F.J., Chen, Y.S., Patel, S., Kokoszka, J., Brown, M.D., Torroni, A., DePaulo, J.R. and Wallace, D.C. (2000). Mitochondrial DNA Sequence Diversity in Bipolar Affective Disorder. American Journal of Psychiatry, 157(7), 1058-1064.
• Ordóñez, A.C., Fregel, R., Trujillo-Mederos, A., Hervella, M., de-la-Rúa, C. and Arnay-de-la-Rosa, M. (2017). Genetic studies on the prehispanic population buried in Punta Azul cave (El Hierro, Canary Islands). Journal of Archaeological Science, 78, 20-28.
• Pereira, L., Gonçalves, J., Franco-Duarte, R., Silva, J., Rocha, T., Arnold, C., Richards, M. and Macaulay, V. (2007). No Evidence for an mtDNA Role in Sperm Motility: Data from Complete Sequencing of Asthenozoospermic Males. Molecular Biology and Evolution, 24(3), 868-874.
• Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J.S., Bezrukov, V. and Blanché, H. (2014). The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging cell, 13(3), 401-407.
• Rusu, I., Modi, A., Vai, S., Pilli, E., Mircea, C., Radu, C., Urduzia, C., Pinter, Z.K., Bodolică, V., Dobrinescu, C. and Hervella, M. (2018). Maternal DNA lineages at the gate of Europe in the 10th century AD. PLoS ONE, 13(3), e0193578+.
• Sequeira, A., Rollins, B., Magnan, C., van Oven, M., Baldi, P., Myers, R.M., Barchas, J.D., Schatzberg, A.F., Watson, S.J., Akil, H. and Bunney, W.E. (2015). Mitochondrial Mutations in Subjects with Psychiatric Disorders. PLoS ONE, 10(5), e0127280.
• Soini, H.K., Moilanen, J.S., Finnila, S. and Majamaa, K. (2012). Mitochondrial DNA sequence variation in Finnish patients with matrilineal diabetes mellitus. BMC research notes, 5(1), 1.
• Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
• Zheng, H. X., Yan, S., Qin, Z. D., & Jin, L. (2012). MtDNA analysis of global populations support that major population expansions began before Neolithic Time. Nature Scientific Reports, 2, -.

Additional Resources

• Ian Logan’s mtDNA Pages
• Ian Logan’s Instructions for mtGenome Genbank Donation
• James Lick’s mtDNA Utility
• The FTDNA Haplogroup Project for Haplogroup H & HV
• The Wikipedia Article for Haplogroup H

mtDNA Consultants

The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.

• DNA Explorers – Robert Sliwinski
• Genetic Genealogy Consultant – Ugo Perego
• Your DNA Guide – Diahan Southard