Haplogroup A22 is a branch on the maternal tree of humanity. Its age is not yet clear. Like its parent though, it traces its origin to Asia.
Research information comes from two published papers and a data set submitted directly to GenBank. One sample comes from an ethnic Han Chinese living in Colorado (Zheng et al., 2011). Two more samples come from a medical study. They do not include demographics, but the study was done in China (Liu et al., 2012). The last sample was directly submitted and comes from China (Jaing et al., 2014).
Geno 2 data does not include a member of this line.
Based on available information, this is definitely an East Asian and very likely a Chinese lineage.
mtDNA Haplogroup A22 Phylotree History
Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.
|16||A22||T6378C C8393T G9123A T9128C||Released 19 Feb 2014|
|17||A22||T6378C C8393T G9123A T9128C||Released 18 Feb 2016|
mtDNA Haplogroup A22 Data Sources
GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.
Note: GenBank results currently use Phylotree build 16. I am working on changing results over to build 17.
|Hg ID||Origin||Publication||Hg BLD16||Hg BLD17||Hg YFull||Missing Variants||Additional Variants|
|Hap5010287||-||Jiang et al., 2014||A22||-||none||A22:152, 309.1C, 315.1C, 523-524d|
|Hap5018185||-||Liu et al., 2012||A22||-||none||A22:309.1C, 315.1C, 523-524d|
|Hap5018278||-||Liu et al., 2012||A22||-||none||A22:309.1C, 315.1C, 523-524d|
|Hap5022233||Zheng et al., 2011||A22||A22:16319||A22:523-524d, 9150, 12200, 16319N, 16519|
Sources & Resources
- Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
- Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
- Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
- - (2014). A Direct Submission to GenBank by Jiang et al., in 2014. , unpublished, unpublished.
- Liu, J., Wang, L.D., Sun, Y.B., Li, E.M., Xu, L.Y., Zhang, Y.P., Yao, Y.G. and Kong, Q.P. (2012). Deciphering the Signature of Selective Constraints on Cancerous Mitochondrial Genome. Molecular Biology and Evolution, 29(4), 1255-1261.
- Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
- Zheng, H.X., Yan, S., Qin, Z.D., Wang, Y., Tan, J.Z., Li, H. and Jin, L. (2011). Major Population Expansion of East Asians Began before Neolithic Time: Evidence of mtDNA Genomes. PLoS ONE, 6(10), e25835+.
- Ian Logan’s mtDNA Pages
- Ian Logan’s Instructions for mtGenome Genbank Donation
- James Lick’s mtDNA Utility
- The FTDNA Haplogroup Project for Haplogroup A2
- The Wikipedia Article for Haplogroup A
The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.
Peoples: Han Chinese | Places: China
Last Updated: Last updated: August 10, 2016 at 17:57 pm