Haplogroup A12a is an Asian branch on the maternal tree of humanity.
Information about the lineage comes from two published study and a citizen science donated sample. The first study includes a lineage member from the Evenk people (Starikovskaya et al., 2005). The second includes someone from the Mansi people (Derenko et al., 2007). Both peoples are from Siberia. The citizen science donated sample does not have demographic information (Behar et al., 2012b).
Geno 2 data does not have a member from this line.
It is difficult to be sure with limited data, but this branch likely originates in Siberia.
mtDNA Haplogroup A12a Phylotree History
Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.
|16||A12a||G1709A A9754G G16039A T16356C||Released 19 Feb 2014|
|17||A12a||G1709A A9754G G16039A T16356C||Released 18 Feb 2016|
mtDNA Haplogroup A12a Data Sources
GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.
Note: GenBank results currently use Phylotree build 16. I am working on changing results over to build 17.
|Hg ID||Origin||Publication||Hg BLD16||Hg BLD17||Hg YFull||Missing Variants||Additional Variants|
|Hap5001613||-||Behar et al., 2012b||A12a||-||none||A12a:309.1C, 315.1C, 523-524d, 4812C, 8839, 9804, 10718, 16188|
|Hap5014377||-||Starikovskaya et al., 2005||A12a||-||none||A12a:309.1C, 315.1C, 523-524d, 3310, 13758, 16519|
|Hap5015911||-||Derenko et al., 2007||A12a||-||none||A12a:309.1C, 315.1C, 523-524d, 15712, 16183C, 16519|
Sources & Resources
- Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
- Derenko, M., Malyarchuk, B., Grzybowski, T., Denisova, G., Dambueva, I., Perkova, M., Dorzhu, C., Luzina, F., Lee, H.K., Vanecek, T. and Villems, R. (2007). Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations. American journal of human genetics, 81(5), 1025-1041.
- Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
- Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
- Starikovskaya, E.B., Sukernik, R.I., Derbeneva, O.A., Volodko, N.V., Ruiz‐Pesini, E., Torroni, A., Brown, M.D., Lott, M.T., Hosseini, S.H., Huoponen, K. and Wallace, D.C. (2005). Mitochondrial DNA Diversity in Indigenous Populations of the Southern Extent of Siberia, and the Origins of Native American Haplogroups. Annals of Human Genetics, 69(1), 67-89.
- Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
- Ian Logan’s mtDNA Pages
- Ian Logan’s Instructions for mtGenome Genbank Donation
- James Lick’s mtDNA Utility
- The FTDNA Haplogroup Project for Haplogroup A2
- The Wikipedia Article for Haplogroup A
The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.
Peoples: Evenk and Mansi | Places: Siberia
Last Updated: [lastupdated]