Summary

Age: 12,953.8 ± 2,580.2; CI=95% (Behar et al., 2012b)
Origin: The Americas
Mutations: T3396C C4025T G6285A A8946G C9458T A16241G
Parent Branch: D4h3
Descendant branch(s): D4h3a1 D4h3a2 D4h3a3 D4h3a4 D4h3a5 D4h3a6 D4h3a7 D4h3a8 D4h3a9

Background

Haplogroup D4h3a is a branch on the maternal tree of human kind. The woman who founded this line lived between 10,400 and 15,500 years ago (Behar et al 2012b).

mtDNA Haplogroup D4h3a Phylotree History

Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.

mtDNA Haplogroup D4h3a Data Sources

GenBank Samples

GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.

Note: GenBank results currently use Phylotree build 16. I am working on changing resuts over to build 17.

Geno 2.0 Data

Data from Geno 2.0 is derived from the The National Geographic Society’s Genographic Project — the DAR. The Hg ID is specific to this site and is used to protect the identities of those who take part in Genographic research. Birth Country, Mother's Birth Country, and Maternal Grandmother's Birth Country have been normalized from DAR database fields. The Maternal Origin is determined based on the three previous fields.

Note: Geno 2.0 results currently use Phylotree build 16. I am working on changing resuts over to build 17.

If you use the information in this table, please credit both this site and The National Geographic Society’s Genographic Project.

Sources & Resources

Related Sources

• Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American journal of human genetics, 90(4), 675-684.
• Duggan, A.T., Harris, A.J., Marciniak, S., Marshall, I., Kuch, M., Kitchen, A., Renaud, G., Southon, J., Fuller, B., Young, J. and Fiedel, S. (2017). Genetic Discontinuity between the Maritime Archaic and Beothuk Populations in Newfoundland, Canada. Current Biology, -, -.
• Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
• Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
• Hartmann, A., Thieme, M., Nanduri, L.K., Stempfl, T., Moehle, C., Kivisild, T. and Oefner, P.J. (2008). Validation of microarray-based resequencing of 93 worldwide mitochondrial genomes. Human mutation, 30(1), 115-122.
• Perego, U.A., Achilli, A., Angerhofer, N., Accetturo, M., Pala, M., Olivieri, A., Kashani, B.H., Ritchie, K.H., Scozzari, R., Kong, Q.P. and Myres, N.M. (2009). Distinctive Paleo-Indian Migration Routes from Beringia Marked by Two Rare mtDNA Haplogroups. Current Biology, 19(1), 1-8.
• Tamm, E., Kivisild, T., Reidla, M., Metspalu, M., Smith, D.G., Mulligan, C.J., Bravi, C.M., Rickards, O., Martinez-Labarga, C., Khusnutdinova, E.K. and Fedorova, S.A. (2007). Beringian Standstill and Spread of Native American Founders. PLoS ONE, 2(9), e829.
• Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.

Additional Resources

• Ian Logan's mtDNA Pages
• Ian Logan's Instructions for mtGenome Genbank Donation
• James Lick's mtDNA Utility
• The FTDNA Haplogroup Project for Haplogroup D
• The Wikipedia Article for Haplogroup D

mtDNA Consultants

The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.

• DNA Explorers – Robert Sliwinski
• Genetic Genealogy Consultant – Ugo Perego
• Your DNA Guide – Diahan Southard