Sample Details for Hap5018200

ID

Hg ID: Hap5018200, GenBank ID: JF824906.2

Haplogroup

Phylotree BLD 16: B4i, Phylotree BLD 17: , YFull: B4i*

Publication

Published in: Liu et al., 2012 | Liu, J., Wang, L.D., Sun, Y.B., Li, E.M., Xu, L.Y., Zhang, Y.P., Yao, Y.G. and Kong, Q.P. (2012). Deciphering the Signature of Selective Constraints on Cancerous Mitochondrial Genome. Molecular Biology and Evolution, 29(4), 1255-1261.

In accordance with the hypothesis that cancer formation is a process of somatic evolution driven by natural selection, signature of positive selection has been detected on a number of cancer-related nuclear genes. It remains, however, controversial whether a similar selective pressure has also acted on mitochondrial DNA (mtDNA), a small molecule in mitochondrion that may play an important role in tumorigenesis by altering oxidative phosphorylation.

Sample source link: http://www.ncbi.nlm.nih.gov/nuccore/JF824906.2

Origin:

Publication Notes: CN181

Results Profile

RSRS Haplotype:

146, 195, 247, 309.1CC, 315.1C, 523-524d, 769, 825T, 1018, 2758, 2885, 3594, 4104, 4312, 6302, 7146, 7256, 7521, 8281-8289d, 8468, 8655, 8701, 9540, 10398, 10664, 10688, 10810, 10873, 10915, 11914, 12654, 12705, 13105, 13276, 13506, 13650, 16129, 16182C, 16183C, 16187, 16217, 16223, 16230, 16246, 16261, 16278, 16311, 16360

rCRS Haplotype:

Coming soon…

FASTA Profile:


Phylotree Build 17 Analysis

Missing Variants: B4i:152

Additional Variants: B4i:309.1CC, 315.1C, 523-524d, 12654, 16182C, 16183C, 16246, 16360


Last Updated: 2016/06/29 10:51:00 PM

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