Sample Details for Hap5012935

ID

Hg ID: Hap5012935, GenBank ID: JX153240.1

Haplogroup

Phylotree BLD 16: K1c1c, Phylotree BLD 17: , YFull: K1c1c

Publication

Published in: Raule et al., 2014 | Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J.S., Bezrukov, V. and Blanché, H. (2014). The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging cell, 13(3), 401-407.

To re-examine the correlation between mtDNA variability and longevity, we examined mtDNAs from samples obtained from over 2200 ultranonagenarians (and an equal number of controls) collected within the framework of the GEHA EU project. The samples were categorized by high-resolution classification, while about 1300 mtDNA molecules (650 ultranonagenarians and an equal number of controls) were completely sequenced. Sequences, unlike standard haplogroup analysis, made possible to evaluate for the first time the cumulative effects of specific, concomitant mtDNA mutations, including those that per se have a low, or very low, impact.

Sample source link: http://www.ncbi.nlm.nih.gov/nuccore/JX153240.1

Origin: Finland

Publication Notes: 1999767

Results Profile

RSRS Haplotype:

247, 315.1C, 498d, 769, 825T, 1018, 1189, 1811, 2758, 2885, 3480, 3594, 4104, 4312, 7146, 7256, 7521, 8468, 8655, 8701, 9055, 9093, 9540, 9698, 9903, 10398, 10550, 10664, 10688, 10810, 10873, 10915, 11299, 11377, 11467, 11914, 12308, 12372, 12705, 13105, 13276, 13506, 13650, 14167, 14798, 16129, 16187, 16189, 16223, 16224, 16230, 16278

rCRS Haplotype:

Coming soon…

FASTA Profile:


Phylotree Build 17 Analysis

Missing Variants: K1c1c:195

Additional Variants: K1c1c:315.1C, 10398


Last Updated: 2016/06/29 10:51:00 PM

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