The YWHAZ gene codes for the production of a protein called 14-3-3 zeta. This protein has many important functions in the body, including helping other proteins to do their jobs and keeping other proteins in the right shape. The YWHAZ gene therefore plays a role in the proper functioning of various processes in the body that involve the 14-3-3 zeta protein.
The 14-3-3 zeta protein has many important functions in the body. It is involved in a variety of processes, including:
- Regulating the activity of other proteins: 14-3-3 zeta can bind to and regulate the activity of various enzymes, receptors, and other proteins in the body.
- Maintaining protein stability: 14-3-3 zeta helps to keep other proteins in their proper shape, which is necessary for their proper function.
- Modulating signaling pathways: 14-3-3 zeta can interact with and modulate signaling pathways, which are pathways in cells that transmit signals from outside the cell to the inside.
- Involved in cell division: 14-3-3 zeta is involved in the regulation of cell division, which is the process by which cells divide and replicate themselves.
- Involved in brain development: 14-3-3 zeta is expressed at high levels in the developing brain, and it has been shown to play a role in brain development.
- Involved in cancer: Abnormalities in the expression or function of 14-3-3 zeta have been observed in various types of cancer, and it is thought to play a role in the development and progression of cancer.
Sources & Resources
- Genetics Home Reference – National Institutes of Health (NIH) – https://ghr.nlm.nih.gov/gene/YWHAZ – Provides a general overview of the YWHAZ gene and its role in the body.
- YWHAZ – GeneCards – https://www.genecards.org/cgi-bin/carddisp.pl?gene=YWHAZ – A database of human genes and proteins that provides detailed information about the YWHAZ gene and its functions.
- YWHAZ: Molecular Function – UniProt – https://www.uniprot.org/uniprot/Q9Y2Y7#function – A database of protein information that describes the molecular function of the YWHAZ protein.
- YWHAZ gene – Wikipedia – https://en.wikipedia.org/wiki/YWHAZ_gene – A general overview of the YWHAZ gene, including its functions and role in disease.
- YWHAZ – NCBI Gene – https://www.ncbi.nlm.nih.gov/gene/8741 – A database of genetic information from the National Center for Biotechnology Information (NCBI) that provides information about the YWHAZ gene and its role in health and disease.