D9S919 is a short tandem repeat (STR) marker that is used in forensic DNA analysis. STRs are repeating sequences of DNA that are highly variable in length and are useful for identifying individuals based on the unique combination of STR markers that they carry. D9S919 is located on chromosome 9 and is one of 13 core STR markers used in the Combined DNA Index System (CODIS), a database maintained by the Federal Bureau of Investigations (FBI) that is used to store and compare DNA profiles from crime scenes, missing persons, and other forensic evidence.
In forensic DNA analysis, samples of DNA are obtained from crime scenes, suspects, or other sources and are analyzed for the presence of specific STR markers. The resulting STR profiles are compared to those in the CODIS database to identify potential matches and assist in criminal investigations. STR markers, including D9S919, are highly specific and are able to accurately identify individuals with a high degree of certainty.
In addition to its use in forensic DNA analysis, D9S919 has also been studied in the context of genetic research. It has been identified as a marker for certain genetic conditions and has been used in studies examining the genetic basis of diseases such as breast cancer, schizophrenia, and Parkinson’s disease.
Sources & Resources
- GeneCards: D9S919 Gene – Card with Gene Information, Chromosome Location, and Links to Other Databases https://www.genecards.org/cgi-bin/carddisp.pl?gene=D9S919 GeneCards is a database of human genes that provides comprehensive, integrative genomic information.
- The Genetics Home Reference: D9S919 Gene – Genetics Home Reference – NIH https://ghr.nlm.nih.gov/gene/D9S919 The Genetics Home Reference is a resource provided by the National Institutes of Health that provides information about genetic conditions and the genes responsible for them.
- STRBase: D9S919 – STR Profile Report http://www.cstl.nist.gov/strbase/findProfile.do?profileId=D9S919 STRBase is a database of short tandem repeat (STR) markers used in forensic DNA analysis.
- The CODIS Loci: D9S919 https://www.fbi.gov/services/laboratory/biometric-analysis/codis/codis-and-ndis-fact-sheet/codis-loci The CODIS Loci is a webpage provided by the Federal Bureau of Investigations (FBI) that provides information about the 13 core short tandem repeat (STR) loci used in the Combined DNA Index System (CODIS).
- Wikipedia: D9S919 – Wikipedia https://en.wikipedia.org/wiki/D9S919 Wikipedia is a free online encyclopedia that provides information on a wide range of topics, including D9S919.
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