Haplotype diversity of 17 Y-chromosome STR loci in Han population from different areas of Sichuan Province, Southwest China

The distribution of 17 Y-chromosome short tandem repeat (STR) loci, included in the AmpFlSTR®Yfiler™ amplification kit, were analyzed in six different samplings (N = 878) from Sichuan, China.

2018-01-10T15:17:15+00:00 January 15th, 2018|

Multicentre study of Y chromosome microdeletions in 1,808 Chinese infertile males using multiplex and real‐time polymerase chain reaction

Azoospermia factor (AZF) genes on the long arm of the human Y chromosome are involved in spermatogenesis, and microdeletions in the AZF region have been recognised to be the second major genetic cause of spermatogenetic failure resulting in male infertility.

2018-01-10T14:57:32+00:00 January 14th, 2018|

Genetic trail for the early migrations of Aisin Gioro, the imperial house of the Qing dynasty

To clarify the origin of Aisin Gioro clan, we conducted whole Y-chromosome sequencing on three samples and Y-single-nucleotide polymorphism (Y-SNP) genotyping on other four samples beside those reported in previous work.

2018-01-10T14:36:16+00:00 January 12th, 2018|

Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes

Here, we investigated the distribution of Y chromosome variation along administrative as well as ethnic divisions in the mainland territory of the People’s Republic of China, including 28 administrative regions and 19 recognized Chinese nationalities, to assess the impact of recent demographic processes.

2017-12-15T07:46:49+00:00 December 15th, 2017|

Genetic diversity and phylogenetic study of the Chinese Gelao ethnic minority via 23 Y-STR loci

Haplotype diversity for 23 Y chromosomal short tandem repeat (Y-STR) loci included in the PowerPlex® Y23 System was analyzed in the Chinese Gelao minority group of 234 unrelated males living in Daozhen Gelao-Miao Autonomous County in Guizhou Province, southwest China.

2017-11-22T11:14:57+00:00 November 22nd, 2017|

Phylogeography of Y-chromosome haplogroup O3a2b2-N6 reveals patrilineal traces of Austronesian populations on the eastern coastal regions of Asia

We propose- that the O3a2b2a2b-B451 lineage represents a genetic connection between ancestors of Austronesian populations and ancient populations in North China, where foxtail millet was domesticated about 11,000 years ago.

2018-02-17T04:26:49+00:00 April 11th, 2017|

Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui

In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province.

2016-12-21T12:57:39+00:00 December 21st, 2016|

Genetic diversity of two Neolithic populations provides evidence of farming expansions in North China

The West Liao River Valley and the Yellow River Valley are recognized Neolithic farming centers in North China. The population dynamics between these two centers have significantly contributed to the present-day genetic patterns and the agricultural advances of North China.

2016-09-26T13:23:37+00:00 September 5th, 2016|

Uncovering the Profile of Somatic mtDNA Mutations in Chinese Colorectal Cancer Patients

In the past decade, a high incidence of somatic mitochondrial DNA (mtDNA) mutations has been observed, mostly based on a fraction of the molecule, in various cancerous tissues; nevertheless, some of them were queried due to problems in data quality.

2018-02-17T04:51:11+00:00 July 3rd, 2016|