Genetic characterization of four Brazilian states with 25 Yfiler®Plus markers

The genetic composition of Brazil is known to vary through 5 geopolitical regions: South, Southeast, North, Northeast and Central-west. Therefore, for this study, samples from Maranhão, Espírito Santo, São Paulo and Rio Grande do Sul were characterized for the Y-STR markers present in YfilerPlus kit, to evaluate if diversity increases with the enlargement of the Yfiler set, and if significant differences exists among populations.

2017-10-19T07:23:06+00:00 October 19th, 2017|

Exploring the mitochondrial DNA variability of the Amazonian Yanomami

The aim of this study was to explore the mitochondrial variability in the Yanomami population to reconstruct its demographic history and explore its genetic composition in relation to its cultural and linguistic features.

2017-01-20T16:49:48+00:00 January 20th, 2017|

Inferring paternal history of rural African-derived Brazilian populations from Y chromosomes

Quilombo remnants are relics of communities founded by runaway or abandoned African slaves, but often with subsequent extensive and complex admixture patterns with European and Native Americans. We combine a genetic study of Y-chromosome markers with anthropological surveys in order to obtain a portrait of quilombo structure and history in the region that has the largest number of quilombo remnants in the state of São Paulo.

2017-01-20T12:15:39+00:00 January 20th, 2017|

LETTER: On the use of Chinese population as a proxy of Amerindian ancestors in genetic admixture studies with Latin American populations

We read the recent article of Magalhães da Silva et al1 reporting the correlation between biogeographic ancestries, estimated using 30 ancestry informative markers (AIMs), and self-reported skin color in two different Brazilian Northeastern populations (Fortaleza and Salvador, capitals of the states of Ceará and Bahia, respectively). The authors observed that African ancestry is more correlated in the sample from Salvador than in the one from Fortaleza and that the use of different African populations as proxies of the Brazilian’s African ancestors may influence the results....

2016-06-16T09:45:36+00:00 June 16th, 2016|

A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set

The Brazilian population is considered to be highly admixed. The main contributing ancestral populations were European and African, with Amerindians contributing to a lesser extent. The aims of this study were to provide a resource for determining and quantifying individual continental ancestry using the smallest number of SNPs possible, thus allowing for a cost- and time-efficient strategy for genomic ancestry determination.

2016-06-16T09:21:14+00:00 June 16th, 2016|


Haplogroup A2 is an Native Americas branch on the maternal tree of human kind. The woman who founded this line lived between 13,900 and 17,400 years ago (Behar et al 2012b).

2017-10-16T09:01:10+00:00 June 6th, 2016|

Disclosing the Genetic Structure of Brazil through Analysis of Male Lineages with Highly Discriminating Haplotypes

In a large variety of genetic studies, probabilistic inferences are made based on information available in population databases. The accuracy of the estimates based on population samples are highly dependent on the number of chromosomes being analyzed as well as the correct representation of the reference population. For frequency calculations the size of a database is especially critical for hapl

2018-02-17T18:12:40+00:00 December 31st, 2012|