Genetic differentiation between upland and lowland populations shapes the Y-chromosomal landscape of West Asia

Here, we analyzed 598 Y-chromosomes from two West Asian subregions—Transcaucasia and the Armenian plateau—using 40 Y-SNPs and 17 Y-STRs and combined them with previously published data from the region.

2017-03-15T12:02:51+00:00 March 14th, 2017|

Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations

We show that Armenian diversity can be explained by several mixtures of Eurasian populations that occurred between ~3000 and ~2000 bce, a period characterized by major population migrations after the domestication of the horse, appearance of chariots, and the rise of advanced civilizations in the Near East. However, genetic signals of population mixture cease after ~1200 bce when Bronze Age civilizations in the Eastern Mediterranean world suddenly and violently collapsed. Armenians have since remained isolated and genetic structure within the population developed ~500 years ago when Armenia was divided between the Ottomans and the Safavid Empire in Iran. Finally, we show that Armenians have higher genetic affinity to Neolithic Europeans than other present-day Near Easterners, and that 29% of Armenian ancestry may originate from an ancestral population that is best represented by Neolithic Europeans.

2016-06-16T08:37:31+00:00 June 16th, 2016|

High-throughput sequencing of complete human mtDNA genomes from the Caucasus and West Asia: high diversity and demographic inferences

To investigate the demographic history of human populations from the Caucasus and surrounding regions, we used high-throughput sequencing to generate 147 complete mtDNA genome sequences from random samples of individuals from three groups from the Caucasus (Armenians, Azeri and Georgians), and one group each from Iran and Turkey.

2016-07-29T09:28:16+00:00 December 31st, 2011|

Genetic Affinity between the Armenian Yezidis and the Iraqi Kurds

The Yezidi community in Armenia has been formed during last two-three centuries as a consequence of several waves of migration. Due to the esoteric character of the community, the Yezidis have been reproductively isolated from neighbouring populations for centuries, which has left significant traces in their genetic structure. Our results based on the analysis of patrilineal genetic lineages demon

2017-01-19T14:51:01+00:00 December 31st, 2010|

Armenian Y chromosome haplotypes reveal strong regional structure within a single ethno-national group

Armenia has been little-studied genetically, even though it is situated in an important area with respect to theories of ancient Middle Eastern population expansion and the spread of Indo-European languages. We screened 734 Armenian males for 11 biallelic and 6 microsatellite Y chromosome markers, segregated them according to paternal grandparental region of birth within or close to Armenia, and c

2017-01-19T14:51:19+00:00 December 31st, 2001|