Haplogroup D4a1e is a branch on the maternal tree of human kind. The woman who founded this line lived between 1,600 and 8,000 years ago (Behar et al 2012b).
Phylotree.org is the maternal (mtDNA) tree of humanity. It is maintained by Dr. Mannis Van Oven. Each build is a major update to the tree. The current build is #17.
|07||D4a1e||7364 16256||Released 10 Nov 2009|
|08||D4a1e||7364 16256||Released 21 Mar 2010|
|09||D4a1e||7364 16256||Released 20 Jun 2010|
|10||D4a1e||7364 16256||Released 10 Aug 2010|
|11||D4a1e||7364 16256||Released 7 Feb 2011|
|12||D4a1e||7364 16256||Released 20 Jul 2011|
|13||D4a1e||7364 16256||Released 28 Dec 2011; Last Build to use the rCRS|
|14||D4a1e||A7364G C16256T||Released 5 Apr 2012; First version to use the RSRS|
|15||D4a1e||A7364G C16256T||Released 30 Sep 2012|
|16||D4a1e||A7364G C16256T||Released 19 Feb 2014|
|17||D4a1e||A7364G C16256T||Released 18 Feb 2016|
GenBank is a database of genetic sequence data. It is run by the United States National Institute of Health. It serves as the main repository for mtDNA full sequence profiles. Samples come both from published academic literature and donations from genetic genealogy community members. In addition to GenBank samples, listings below may include other samples published but not submitted to GenBank such as those from the HapMap project.
Note: GenBank results currently use Phylotree build 16. I am working on changing resuts over to build 17.
|Hg ID||Publication||Missing Variants||Additional Variants|
|Hap5005506||Bilal et al., 2008||none||D4a1e:315.1C, 523-524d, 6755, 7334, 8614, 9254|
|Hap5005813||Chandrasekar et al., 2009||D4a1e:14979||D4a1e:315.1C, 3705, 15839|
|Hap5011332||Ko et al., 2014||none||D4a1e:723, 13140, 16299|
|Hap5014937||Tanaka et al., 2004||none||D4a1e:315.1C, 523-524d, 8614, 9254|
|Hap5018121||Liu et al., 2012||none||D4a1e:72, 315.1C, 745|
|Hap5018214||Liu et al., 2012||none||D4a1e:72, 315.1C, 745|
Geno 2.0 Data
Data from Geno 2.0 is derived from the The National Geographic Society’s Genographic Project — the DAR. The Hg ID is specific to this site and is used to protect the identities of those who take part in Genographic research. Birth Country, Mother's Birth Country, and Maternal Grandmother's Birth Country have been normalized from DAR database fields. The Maternal Origin is determined based on the three previous fields.
Note: Geno 2.0 results currently use Phylotree build 16. I am working on changing resuts over to build 17.
|Hap10046407||United States||United States||Japan||Japan|
If you use the information in this table, please credit both this site and The National Geographic Society’s Genographic Project.
- Behar, D.M., van Oven, M., Rosset, S., Metspalu, M., Loogväli, E.L., Silva, N.M., Kivisild, T., Torroni, A. and Villems, R. (2012). A “Copernican” reassessment of the human mitochondrial DNA tree from its root. American Journal of Human Genetics, 90(4), 675-684.
- Bilal, E., Rabadan, R., Alexe, G., Fuku, N., Ueno, H., Nishigaki, Y., Fujita, Y., Ito, M., Arai, Y., Hirose, N. and Ruckenstein, A. (2008). Mitochondrial DNA Haplogroup D4a Is a Marker for Extreme Longevity in Japan. PLoS ONE, 3(6), e2421.
- Chandrasekar, A., Kumar, S., Sreenath, J., Sarkar, B.N., Urade, B.P., Mallick, S., Bandopadhyay, S.S., Barua, P., Barik, S.S., Basu, D. and Kiran, U. (2009). Updating Phylogeny of Mitochondrial DNA Macrohaplogroup M in India: Dispersal of Modern Human in South Asian Corridor. PLoS ONE, 4(10), e7447+.
- Fan, L., & Yao, Y. G. (2011). MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11(2), 351-356.
- Fan, L., & Yao, Y. G. (2013). An update to MitoTool: using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13(4), 360-363.
- Ko, A.M.S., Chen, C.Y., Fu, Q., Delfin, F., Li, M., Chiu, H.L., Stoneking, M. and Ko, Y.C. (2014). Early Austronesians: Into and Out Of Taiwan. American Journal of Human Genetics, 94(3), 426-436.
- Liu, J., Wang, L.D., Sun, Y.B., Li, E.M., Xu, L.Y., Zhang, Y.P., Yao, Y.G. and Kong, Q.P. (2012). Deciphering the Signature of Selective Constraints on Cancerous Mitochondrial Genome. Molecular Biology and Evolution, 29(4), 1255-1261.
- Tanaka, M., Cabrera, V.M., González, A.M., Larruga, J.M., Takeyasu, T., Fuku, N., Guo, L.J., Hirose, R., Fujita, Y., Kurata, M. & Shinoda, K.I. (2004). Mitochondrial Genome Variation in Eastern Asia and the Peopling of Japan. Genome Research, 14(10a), 1832-1850.
- Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human mutation, 30(2), E386-E394.
- Ian Logan's mtDNA Pages
- Ian Logan's Instructions for mtGenome Genbank Donation
- James Lick's mtDNA Utility
- The FTDNA Haplogroup Project for Haplogroup D
- The Wikipedia Article for Haplogroup D
The following members of the community offer paid consulting for those seeking help with mtDNA results. Inclusion on this list is not a recommendation or endorsement of any service.
Last Updated: Last updated: November 30, -0001 at 0:00 am
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