Home/Journal Article Archive
Journal Article Archive 2016-10-14T01:03:42+00:00

Journal Article Archive

A Complete mtDNA Genome of an Early Modern Human from Kostenki, Russia

Journal: Current Biology | Year: 2010

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

Journal: Nature Communications | Year: 2016

Abstract:

The African Diaspora in the Western Hemisphere represents one of the largest forced migrations in history and had a profound impact on genetic diversity in modern populations. To date, the fine-scale population structure of descendants of the African Diaspora remains largely uncharacterized. Here we present genetic variation from deeply sequenced genomes of 642 individuals from North and South American, Caribbean and West African populations, substantially increasing the lexicon of human genomic variation and suggesting much variation remains to be discovered in African-admixed populations in the Americas. We summarize genetic variation in these populations, quantifying the postcolonial sex-biased European gene flow across multiple regions. Moreover, we refine estimates on the burden of deleterious variants carried across populations and how this varies with African ancestry. Our data are an important resource for empowering disease mapping studies in African-admixed individuals and will facilitate gene discovery for diseases disproportionately affecting individuals of African ancestry.

Peoples: African-admixed individuals | Places: Africa, North America, and South America | Topics: African ancestry | DNA Type: Autosomal DNA

A counter-clockwise northern route of the Y-chromosome haplogroup N from Southeast Asia towards Europe

Journal: European Journal of Human Genetics | Year: 2006

Abstract:

A large part of Y chromosome lineages in East European and East Asian human populations belong to haplogroup (hg) NO, which is composed of two sister clades N-M231 and O-M175. The O-clade is relatively old (around 30 thousand years (ky)) and encompasses the vast majority of east and Southeast Asian male lineages, as well as significant proportion of those in Oceanian males. On the other hand, our detailed analysis of hg N suggests that its high frequency in east Europe is due to its more recent expansion westward on a counter-clock northern route from inner Asia/southern Siberia, approximately 12–14 ky ago. The widespread presence of hg N in Siberia, together with its absence in Native Americans, implies its spread happened after the founder event for the Americas. The most frequent subclade N3, arose probably in the region of present day China, and subsequently experienced serial bottlenecks in Siberia and secondary expansions in eastern Europe. Another branch, N2, forms two distinctive subclusters of STR haplotypes, Asian (N2-A) and European (N2-E), the latter now mostly distributed in Finno-Ugric and related populations. These phylogeographic patterns provide evidence consistent with male-mediated counter-clockwise late Pleistocene–Holocene migratory trajectories toward Northwestern Europe from an ancestral East Asian source of Paleolithic heritage.

Peoples: Finno-Ugric | Places: East Asia and Europe | Topics: Migrations | DNA Type: Y-DNA

A Direct Submission to GenBank by Trejaut et al., 2005

Journal: | Year: 2005

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Fayzulin and Alexeyev in 2011

Journal: | Year: 2011

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Genebase 2012

Journal: GenBank Only | Year: 2012

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Gómez-Durán et al., in 2011

Journal: | Year: 2011

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Illeperuma et al., in 2011

Journal: | Year: 2011

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Illeperuma et al., in 2011

Journal: | Year: 2011

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

A Direct Submission to GenBank by Imanishi et al., 2011

Journal: GenBank Only | Year: 2011

Abstract:

Peoples: | Places: | Topics: | DNA Type: mtDNA

« First ‹ Previous 1 2 3 4 12 102 113 Next › Last »